Birden fazla yolla et ve et ürünlerinde meydana gelebilen Polisiklik aromatik hidrokarbonlar hakkında ingilizce makale...

 1. Introduction
Polycyclic aromatic hydrocarbons (PAHs) are a group of compounds comprised of fused aromatic rings. PAHs containing up to four fused benzene rings are known as light PAHs and those containing more than four benzene rings are called heavy PAHs. Heavy PAHs are more stable and more toxic than light ones (Wenzl, Simon,
Kleiner, & Anklam, 2006). Light PAHs are more volatile, water soluble and less lipophilic than the heavy PAHs (Ferrarese, Andreottola, Irina, & Oprea, 2008; Wild & Jones, 1994). According to the Scientific Committee on Food (2002), 15 PAHs showed clear evidence of mutagenicity/genotoxicity in somatic cells in experimental
animals in vivo. They may be regarded as potentially genotoxic and carcinogenic to humans their carcinogenicity is initiated by their metabolic conversion in mammalian cells to diolepoxides that bind covalently to cellular macromolecules, including DNA,
causing errors in DNA replication and mutation (Phillips & Grover, 1994).


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