(ingilizce kaynak)

Introduction
Investigations during the past 30 years on the occurrence of N-nitrosamines and the etiology of these compounds in human cancer began with two important discoveries. In 1956, the UK scientists David Barnes and Peter Magee reported N-nitrosodimethylamine (NDMA) as a carcinogen in experimental animals. In Norway in the early 1960s, NDM proved to be the causative agent in the death ofich had been fed nitrite-preserved
fish meal. The nitrite had reacted with amines in the fish meal to produce lethal amounts of NDMA. Since nitrite is added to human foods, particularly
cured meats, and amines occur commonly in most foods, this raised the question as to whether carcinogenic nitrosamines might also form in human foods. This article summarizes the results of the many investigations which have addressed this important issue.

Dosya türü : pdf

Dosya şifresi : www.forumfood.net